Sacran

Sacran is a natural giant molecular polysaccharide extracted from the algae, Aphanithece Sacrum, which lives in clear spring water from underflow water in ‘Aso’ region. Aphanothece sacrum is a highly valuable plant that can only live in special regions where the water is pristine and flows slowly.

APPLICATIONS

Lotions
Milky Lotions
Creams
Skin-care Products
Makeup Products

Key characteristics

Natural giant molecular
- Natural polysaccharide extracted from Aphanothece sacrum found in Kumamoto and Fukuoka prefectures
Moisturizing effect
- 10 – fold higher moisture retention capacity compared to hyaluronic acid
Protective membrane formation
- Functions as a barrier to protect skin from external stimulus
Anti-inflammatory effect

Product	INCI Name	Other Ingredients
SACRAN B	APHANOTHECE SACRUM POLYSACCHARIDES	Water and Butylene Glycol
SACRAN F	APHANOTHECE SACRUM POLYSACCHARIDES	Water and Phenoxyethanol

CHARACTERISTICS OF SACRAN

Super-macromolecule with molecular weight of about 20 millon
Anionic polysaccharide with about 11% of sulfate groups and 12% of carboxyl groups per sugar chain
Eleven types of monosaccharides including glucose, galactose, xylose and fucose have been identified as components and sacran a novel monosaccharide, sulfated muramic acid
Aphanothece sacrum is a prokaryote but sacran is predicted to have a similar structure to mucopolysaccharides produced eukaryotes and is anticipated to have a range of physiological activities

TEMPRETURE STABILITY

Xanthan gum decreases in viscosity when heated. On the other hand, sacran does not show any change in viscosity due to heating and remains stable. This difference in viscosity was confirmed to increase when heated.

Increase in viscosity due to the addition of salt

Addition of various concentration of salts (NaCl) to 1% (w/v) sacran solution resulted in an increase in sacran viscosity. The maximum viscosity was reached when the concentration was equivalent (about 0.9%) to physiological salt solution.

WATER RETENTION CAPACITY

Using the improved tea bag method, a water retention assay was conducted for sacran, hyaluronic acid and xanthan gum. As a result of measuring the volume (ml) of water retained by 1 g (dry weight) of each sample, sacran was found to have a water retention capacity exceeding 6000-fold its own weight. Furthermore, compared to hyaluronic acid and xanthan gum, it was confirmed to have a water retention capacity 5 times and 10 times greater than hyaluronic acid when using pure water and salt water for the assay, respectively.

BARRIER FUNCTION

Sacran solution (concentration: 10 ppm) was applied to mica and observed by atomic force microscopy (AFM). Sacran found to form a mesh-like film and to be a macromolecule with a length of 12 µm

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